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Harvard gene-editing tool “sneaks” DNA into cells without making cuts

A new genetic engineering tool called Retron Library Recombineering (RLR) could be a cleaner alternative to CRISPR

CRISPR-Cas9 is a revolutionary gene-editing tool, but it’s not without its downsides. Now, scientists at Harvard have demonstrated an alternative genetic engineering system called Retron Library Recombineering (RLR), which works without cutting DNA and can be quickly applied to huge populations of cells.

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Category: Biology, Science

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